Sonic Hedgehog Promotes Tumor Cell Survival by Inhibiting CDON Pro-Apoptotic Activity

The Hedgehog signaling is a determinant pathway for tumor progression. However, while inhibition of the Hedgehog canonical pathway—Patched–Smoothened–Gli—has proved efficient in human tumors with activating mutations in this pathway, recent clinical data have failed to show any benefit in other canc...

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Detalles Bibliográficos
Autores principales: Delloye-Bourgeois, Céline, Gibert, Benjamin, Rama, Nicolas, Delcros, Jean-Guy, Gadot, Nicolas, Scoazec, Jean-Yves, Krauss, Robert, Bernet, Agnès, Mehlen, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735457/
https://www.ncbi.nlm.nih.gov/pubmed/23940460
http://dx.doi.org/10.1371/journal.pbio.1001623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735457/
https://www.ncbi.nlm.nih.gov/pubmed/23940460
http://dx.doi.org/10.1371/journal.pbio.1001623

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