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Linking Stochastic Fluctuations in Chromatin Structure and Gene Expression
The number of mRNA and protein molecules expressed from a single gene molecule fluctuates over time. These fluctuations have been attributed, in part, to the random transitioning of promoters between transcriptionally active and inactive states, causing transcription to occur in bursts. However, the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735467/ https://www.ncbi.nlm.nih.gov/pubmed/23940458 http://dx.doi.org/10.1371/journal.pbio.1001621 |