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Linking Stochastic Fluctuations in Chromatin Structure and Gene Expression

The number of mRNA and protein molecules expressed from a single gene molecule fluctuates over time. These fluctuations have been attributed, in part, to the random transitioning of promoters between transcriptionally active and inactive states, causing transcription to occur in bursts. However, the...

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Detalles Bibliográficos
Autores principales: Brown, Christopher R., Mao, Changhui, Falkovskaia, Elena, Jurica, Melissa S., Boeger, Hinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735467/
https://www.ncbi.nlm.nih.gov/pubmed/23940458
http://dx.doi.org/10.1371/journal.pbio.1001621