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Concomitant Loss of p120-Catenin and β-Catenin Membrane Expression and Oral Carcinoma Progression with E-Cadherin Reduction

The binding of p120-catenin and β-catenin to the cytoplasmic domain of E-cadherin establishes epithelial cell-cell adhesion. Reduction and loss of catenin expression degrades E-cadherin-mediated carcinoma cell-cell adhesion and causes carcinomas to progress into aggressive states. Since both catenin...

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Detalles Bibliográficos
Autores principales: Sasaya, Kazunobu, Sudo, Haruka, Maeda, Genta, Kawashiri, Shuichi, Imai, Kazushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735538/
https://www.ncbi.nlm.nih.gov/pubmed/23936352
http://dx.doi.org/10.1371/journal.pone.0069777