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Expression of Drug Targets in Patients Treated with Sorafenib, Carboplatin and Paclitaxel

INTRODUCTION: Sorafenib, a multitarget kinase inhibitor, targets members of the mitogen-activated protein kinase (MAPK) pathway and VEGFR kinases. Here we assessed the association between expression of sorafenib targets and biomarkers of taxane sensitivity and response to therapy in pre-treatment tu...

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Detalles Bibliográficos
Autores principales: Jilaveanu, Lucia B., Zhao, Fengmin, Zito, Christopher R., Kirkwood, John M., Nathanson, Katherine L., D'Andrea, Kurt, Wilson, Melissa, Rimm, David L., Flaherty, Keith T., Lee, Sandra J., Kluger, Harriet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735539/
https://www.ncbi.nlm.nih.gov/pubmed/23936348
http://dx.doi.org/10.1371/journal.pone.0069748