Deletion of Thioredoxin Reductase and Effects of Selenite and Selenate Toxicity in Caenorhabditis elegans

Thioredoxin reductase-1 (TRXR-1) is the sole selenoprotein in C. elegans, and selenite is a substrate for thioredoxin reductase, so TRXR-1 may play a role in metabolism of selenium (Se) to toxic forms. To study the role of TRXR in Se toxicity, we cultured C. elegans with deletions of trxr-1, trxr-2,...

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Detalles Bibliográficos
Autores principales: Boehler, Christopher J., Raines, Anna M., Sunde, Roger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735571/
https://www.ncbi.nlm.nih.gov/pubmed/23936512
http://dx.doi.org/10.1371/journal.pone.0071525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735571/
https://www.ncbi.nlm.nih.gov/pubmed/23936512
http://dx.doi.org/10.1371/journal.pone.0071525

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