Cargando…

Deletion of Thioredoxin Reductase and Effects of Selenite and Selenate Toxicity in Caenorhabditis elegans

Thioredoxin reductase-1 (TRXR-1) is the sole selenoprotein in C. elegans, and selenite is a substrate for thioredoxin reductase, so TRXR-1 may play a role in metabolism of selenium (Se) to toxic forms. To study the role of TRXR in Se toxicity, we cultured C. elegans with deletions of trxr-1, trxr-2,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boehler, Christopher J., Raines, Anna M., Sunde, Roger A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735571/ https://www.ncbi.nlm.nih.gov/pubmed/23936512 http://dx.doi.org/10.1371/journal.pone.0071525

Ejemplares similares

Toxic-Selenium and Low-Selenium Transcriptomes in Caenorhabditis elegans: Toxic Selenium Up-Regulates Oxidoreductase and Down-Regulates Cuticle-Associated Genes
por: Boehler, Christopher J., et al.
Publicado: (2014)

Kinetics and mechanism of selenate and selenite removal in solution by green rust-sulfate
por: Onoguchi, Aina, et al.
Publicado: (2019)

The Effect of High Selenite and Selenate Concentrations on Ferric Oxyhydroxides Transformation under Alkaline Conditions
por: Matulová, Michaela, et al.
Publicado: (2021)

Protective Efficacy of Selenite against Lead-Induced Neurotoxicity in Caenorhabditis elegans
por: Li, Wen-Hsuan, et al.
Publicado: (2013)

Difference between Selenite and Selenate in the Regulation of Growth and Physiological Parameters of Nickel-Exposed Lettuce
por: Hawrylak-Nowak, Barbara, et al.
Publicado: (2020)

Functional characterization of thioredoxin 3 (TRX-3), a Caenorhabditis elegans intestine-specific thioredoxin
por: Jiménez-Hidalgo, María, et al.
Publicado: (2014)

Redox-dependent and redox-independent functions of Caenorhabditis elegans thioredoxin 1
por: Sanzo-Machuca, Ángela, et al.
Publicado: (2019)

Selenium Accumulation Characteristics and Biofortification Potentiality in Turnip (Brassica rapa var. rapa) Supplied with Selenite or Selenate
por: Li, Xiong, et al.
Publicado: (2018)

A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity
por: Köhnlein, Karl, et al.
Publicado: (2019)

Effects of High Doses of Selenate, Selenite and Nano-Selenium on Biometrical Characteristics, Yield and Biofortification Levels of Vicia faba L. Cultivars
por: Sindireva, Anna, et al.
Publicado: (2023)

Initial Step of Selenite Reduction via Thioredoxin for Bacterial Selenoprotein Biosynthesis
por: Shimizu, Atsuki, et al.
Publicado: (2021)

Selenate and selenite transporters in proso millet: Genome extensive detection and expression studies under salt stress and selenium
por: Mushtaq, Naveed Ul, et al.
Publicado: (2022)

Deletion of Thioredoxin Reductase Disrupts Redox Homeostasis and Impairs β-Cell Function
por: Stancill, Jennifer S, et al.
Publicado: (2022)

Discriminative Long-Distance Transport of Selenate and Selenite Triggers Glutathione Oxidation in Specific Subcellular Compartments of Root and Shoot Cells in Arabidopsis
por: Khan, Muhammad Sayyar, et al.
Publicado: (2022)

Thioredoxin Reductase and its Inhibitors
por: Saccoccia, Fulvio, et al.
Publicado: (2014)

Selenite Enhances Immune Response against Pseudomonas aeruginosa PA14 via SKN-1 in Caenorhabditis elegans
por: Li, Wen-Hsuan, et al.
Publicado: (2014)

Thioredoxin 1 and Thioredoxin Reductase 1 Redox System Is Dysregulated in Neutrophils of Subjects with Autism: In Vitro Effects of Environmental Toxicant, Methylmercury
por: Alshehri, Samiyah, et al.
Publicado: (2023)

Selenium toxicity but not deficient or super-nutritional selenium status vastly alters the transcriptome in rodents
por: Raines, Anna M, et al.
Publicado: (2011)

The Role of Thioredoxin Reductases in Brain Development
por: Soerensen, Jonna, et al.
Publicado: (2008)

Hepatocyte Hyperproliferation upon Liver-Specific Co-disruption of Thioredoxin-1, Thioredoxin Reductase-1, and Glutathione Reductase
por: Prigge, Justin R., et al.
Publicado: (2017)

Overexpression of chloroplast NADPH-dependent thioredoxin reductase in Arabidopsis enhances leaf growth and elucidates in vivo function of reductase and thioredoxin domains
por: Toivola, Jouni, et al.
Publicado: (2013)

Role of thioredoxin reductase 1 and thioredoxin interacting protein in prognosis of breast cancer
por: Cadenas, Cristina, et al.
Publicado: (2010)

Expression of Thioredoxin/Thioredoxin Reductase System Genes in Aphid-Challenged Maize Seedlings
por: Sytykiewicz, Hubert, et al.
Publicado: (2020)

Biosynthesis of selenate reductase in Salmonella enterica: critical roles for the signal peptide and DmsD
por: Connelly, Katherine R. S, et al.
Publicado: (2016)

Toxicity and Antigenotoxic Effect of Hispolon Derivatives: Role of Structure in Modulating Cellular Redox State and Thioredoxin Reductase
por: Chethna, Pogakula, et al.
Publicado: (2018)

The Glutathione Reductase GSR-1 Determines Stress Tolerance and Longevity in Caenorhabditis elegans
por: Lüersen, Kai, et al.
Publicado: (2013)

Molecular Basis for the Interactions of Human Thioredoxins with Their Respective Reductases
por: Hossain, Md Faruq, et al.
Publicado: (2021)

Acetylation Regulates Thioredoxin Reductase Oligomerization and Activity
por: Wright, David E., et al.
Publicado: (2018)

Characterizing Roles for the Glutathione Reductase, Thioredoxin Reductase and Thioredoxin Peroxidase-Encoding Genes of Magnaporthe oryzae during Rice Blast Disease
por: Fernandez, Jessie, et al.
Publicado: (2014)

Thioredoxin Reductase Activity Predicts Gold Nanoparticle Radiosensitization Effect
por: Penninckx, Sébastien, et al.
Publicado: (2019)

Molecular characterization of ethyl carbamate toxicity in Caenorhabditis elegans
por: Comfort, Jordan J., et al.
Publicado: (2022)

Selenite reduction by Shewanella oneidensis MR-1 is mediated by fumarate reductase in periplasm
por: Li, Dao-Bo, et al.
Publicado: (2014)

CRISPR/Cas9 Methodology for the Generation of Knockout Deletions in Caenorhabditis elegans
por: Au, Vinci, et al.
Publicado: (2018)

Fast genetic mapping using insertion-deletion polymorphisms in Caenorhabditis elegans
por: Hwang, Ho-Yon, et al.
Publicado: (2021)

Cytotoxic and radiosensitising effects of a novel thioredoxin reductase inhibitor in breast cancer
por: Abdullah, Nurul A, et al.
Publicado: (2021)

Cytotoxic and Radiosensitising Effects of a Novel Thioredoxin Reductase Inhibitor in Brain Cancers
por: Yao, Anqi, et al.
Publicado: (2022)

Toxic Effects of Bisphenol A, Propyl Paraben, and Triclosan on Caenorhabditis elegans
por: García-Espiñeira, María Cecilia, et al.
Publicado: (2018)

Neurodevelopmental Toxicity of Polystyrene Nanoplastics in Caenorhabditis elegans and the Regulating Effect of Presenilin
por: Liu, Qianyun, et al.
Publicado: (2020)

Acetaminophen Reactive Intermediates Target Hepatic Thioredoxin Reductase
por: Jan, Yi-Hua, et al.
Publicado: (2014)

Thioredoxin Reductase Is Involved in Development and Pathogenicity in Fusarium graminearum
por: Fan, Xinyue, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_hverp3lq04pbqrbnlr43fg5pru