Role of lysosome rupture in controlling Nlrp3 signaling and necrotic cell death

The Nod-like receptor, Nlrp3, has been linked to inflammatory diseases and adjuvant-mediated immune responses. A wide array of structurally diverse agents does not interact directly with Nlrp3, but is thought to activate the Nlrp3 inflammasome by inducing a common upstream signal, such as lysosome r...

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Detalles Bibliográficos
Autores principales: Lima, Jr., Heriberto, Jacobson, Lee S., Goldberg, Michael F., Chandran, Kartik, Diaz-Griffero, Felipe, Lisanti, Michael P., Brojatsch, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735701/
https://www.ncbi.nlm.nih.gov/pubmed/23708522
http://dx.doi.org/10.4161/cc.24903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735701/
https://www.ncbi.nlm.nih.gov/pubmed/23708522
http://dx.doi.org/10.4161/cc.24903

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