Analgesic effects of the COX-2 inhibitor parecoxib on surgical pain through suppression of spinal ERK signaling

Cyclooxygenase (COX)-2 inhibitors are widely used for postoperative pain control in clinical practice. However, it is unknown whether spinal sensitization is involved in the analgesic effects of COX-2 inhibitors on surgical pain. Extracellular signal-regulated kinase (ERK) in the spinal cord is impl...

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Detalles Bibliográficos
Autores principales: GUO, YA-JING, SHI, XU-DAN, FU, DI, YANG, YONG, WANG, YA-PING, DAI, RU-PING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735898/
https://www.ncbi.nlm.nih.gov/pubmed/23935760
http://dx.doi.org/10.3892/etm.2013.1118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3735898/
https://www.ncbi.nlm.nih.gov/pubmed/23935760
http://dx.doi.org/10.3892/etm.2013.1118

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