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Effect on lifespan of high yield non-myeloablating transplantation of bone marrow from young to old mice

Tissue renewal is a well-known phenomenon by which old and dying-off cells of various tissues of the body are replaced by progeny of local or circulating stem cells (SCs). An interesting question is whether donor SCs are capable to prolong the lifespan of an aging organism by tissue renewal. In this...

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Detalles Bibliográficos
Autores principales: Kovina, Marina V., Zuev, Viktor A., Kagarlitskiy, German O., Khodarovich, Yuriy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736046/
https://www.ncbi.nlm.nih.gov/pubmed/23967009
http://dx.doi.org/10.3389/fgene.2013.00144