Adenosine-A(3) receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes

The A(3)-adenosine receptor (A(3)AR) has recently emerged as a key regulator of neutrophil behaviour. Using a fluorescent A(3)AR ligand, we show that A(3)ARs aggregate in highly polarized immunomodulatory microdomains on human neutrophil membranes. In addition to regulating chemotaxis, A(3)ARs promo...

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Detalles Bibliográficos
Autores principales: Corriden, Ross, Self, Tim, Akong-Moore, Kathryn, Nizet, Victor, Kellam, Barrie, Briddon, Stephen J, Hill, Stephen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Scientific Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736131/
https://www.ncbi.nlm.nih.gov/pubmed/23817552
http://dx.doi.org/10.1038/embor.2013.89

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736131/
https://www.ncbi.nlm.nih.gov/pubmed/23817552
http://dx.doi.org/10.1038/embor.2013.89

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