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Adenosine-A(3) receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes
The A(3)-adenosine receptor (A(3)AR) has recently emerged as a key regulator of neutrophil behaviour. Using a fluorescent A(3)AR ligand, we show that A(3)ARs aggregate in highly polarized immunomodulatory microdomains on human neutrophil membranes. In addition to regulating chemotaxis, A(3)ARs promo...
Autores principales: | Corriden, Ross, Self, Tim, Akong-Moore, Kathryn, Nizet, Victor, Kellam, Barrie, Briddon, Stephen J, Hill, Stephen J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736131/ https://www.ncbi.nlm.nih.gov/pubmed/23817552 http://dx.doi.org/10.1038/embor.2013.89 |
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