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Peripherally Induced Tregs – Role in Immune Homeostasis and Autoimmunity
Thymically derived Foxp3(+) regulatory T cells (tTregs) constitute a unique T cell lineage that is essential for maintaining immune tolerance to self and immune homeostasis. However, Foxp3 can also be turned on in conventional T cells as a consequence of antigen exposure in the periphery, under both...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736167/ https://www.ncbi.nlm.nih.gov/pubmed/23966994 http://dx.doi.org/10.3389/fimmu.2013.00232 |