Cargando…

Peripherally Induced Tregs – Role in Immune Homeostasis and Autoimmunity

Thymically derived Foxp3(+) regulatory T cells (tTregs) constitute a unique T cell lineage that is essential for maintaining immune tolerance to self and immune homeostasis. However, Foxp3 can also be turned on in conventional T cells as a consequence of antigen exposure in the periphery, under both...

Descripción completa

Detalles Bibliográficos
Autores principales: Yadav, Mahesh, Stephan, Stephen, Bluestone, Jeffrey A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736167/
https://www.ncbi.nlm.nih.gov/pubmed/23966994
http://dx.doi.org/10.3389/fimmu.2013.00232