Cargando…
Peripherally Induced Tregs – Role in Immune Homeostasis and Autoimmunity
Thymically derived Foxp3(+) regulatory T cells (tTregs) constitute a unique T cell lineage that is essential for maintaining immune tolerance to self and immune homeostasis. However, Foxp3 can also be turned on in conventional T cells as a consequence of antigen exposure in the periphery, under both...
Autores principales: | Yadav, Mahesh, Stephan, Stephen, Bluestone, Jeffrey A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736167/ https://www.ncbi.nlm.nih.gov/pubmed/23966994 http://dx.doi.org/10.3389/fimmu.2013.00232 |
Ejemplares similares
-
Tregs in Autoimmunity: Insights Into Intrinsic Brake Mechanism Driving Pathogenesis and Immune Homeostasis
por: Bednar, Kyle J., et al.
Publicado: (2022) -
Inducing and Administering Tregs to Treat Human Disease
por: Perdigoto, Ana Luisa, et al.
Publicado: (2016) -
Opportunities for Treg cell therapy for the treatment of human disease
por: Bluestone, Jeffrey A., et al.
Publicado: (2023) -
Treg Heterogeneity, Function, and Homeostasis
por: Shevyrev, Daniil, et al.
Publicado: (2020) -
Harnessing Treg Homeostasis to Optimize Posttransplant Immunity: Current Concepts and Future Perspectives
por: Ikegawa, Shuntaro, et al.
Publicado: (2021)