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Expanded activity of dimer nucleases by combining ZFN and TALEN for genome editing

Our ability to precisely and efficiently edit mammalian and plant genomes has been significantly improved in recent years, partially due to increasing use of designer nucleases that recognize a pre-determined DNA sequence, make a specific DNA double-strand break, and stimulate gene targeting. A pair...

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Detalles Bibliográficos
Autores principales: Yan, Wei, Smith, Cory, Cheng, Linzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736171/
https://www.ncbi.nlm.nih.gov/pubmed/23921522
http://dx.doi.org/10.1038/srep02376