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Expanded activity of dimer nucleases by combining ZFN and TALEN for genome editing
Our ability to precisely and efficiently edit mammalian and plant genomes has been significantly improved in recent years, partially due to increasing use of designer nucleases that recognize a pre-determined DNA sequence, make a specific DNA double-strand break, and stimulate gene targeting. A pair...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736171/ https://www.ncbi.nlm.nih.gov/pubmed/23921522 http://dx.doi.org/10.1038/srep02376 |