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Host genetic background impacts modulation of the TLR4 pathway by RON in tissue-associated macrophages
Toll-like receptors (TLRs) enable metazoans to mount effective innate immune responses to microbial and viral pathogens, as well as to endogenous host-derived ligands. It is understood that genetic background of the host can influence TLR responsiveness, altering susceptibility to pathogen infection...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736205/ https://www.ncbi.nlm.nih.gov/pubmed/23817579 http://dx.doi.org/10.1038/icb.2013.27 |