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Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors

The dynamic organization of signaling cascades inside primary cilia is key to signal propagation. Yet little is known about the dynamics of ciliary membrane proteins besides a possible role for motor-driven Intraflagellar Transport (IFT). To characterize these dynamics, we imaged single molecules of...

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Detalles Bibliográficos
Autores principales: Ye, Fan, Breslow, David K, Koslover, Elena F, Spakowitz, Andrew J, Nelson, W James, Nachury, Maxence V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3736543/
https://www.ncbi.nlm.nih.gov/pubmed/23930224
http://dx.doi.org/10.7554/eLife.00654