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Ocular pharmacokinetics of bimatoprost formulated in DuraSite compared to bimatoprost 0.03% ophthalmic solution in pigmented rabbit eyes

PURPOSE: To compare the aqueous humor (AH) and iris-ciliary body (ICB) concentration of bimatoprost in rabbit eyes treated with ISV-215 (0.03% bimatoprost formulated in DuraSite) with the marketed product bimatoprost 0.03% ophthalmic solution. METHODS: The left eye of rabbits received a single topic...

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Detalles Bibliográficos
Autores principales: Shafiee, Afshin, Bowman, Lyle M, Hou, Eddie, Hosseini, Kamran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737010/
https://www.ncbi.nlm.nih.gov/pubmed/23940414
http://dx.doi.org/10.2147/OPTH.S48766