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Hydrogen atoms in protein structures: high-resolution X-ray diffraction structure of the DFPase

BACKGROUND: Hydrogen atoms represent about half of the total number of atoms in proteins and are often involved in substrate recognition and catalysis. Unfortunately, X-ray protein crystallography at usual resolution fails to access directly their positioning, mainly because light atoms display weak...

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Detalles Bibliográficos
Autores principales: Elias, Mikael, Liebschner, Dorothee, Koepke, Jurgen, Lecomte, Claude, Guillot, Benoit, Jelsch, Christian, Chabriere, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737025/
https://www.ncbi.nlm.nih.gov/pubmed/23915572
http://dx.doi.org/10.1186/1756-0500-6-308