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In-vitro/In-vivo comparison of leuprolide acetate release from an in-situ forming plga system

A poly (lactide-co-glycolide) (PLGA) implant was used to control the release profile of leuprolide acetate (LA) drug. The system is an in-situ polymeric precipitation system. And the formulation consisted of PLGA polymer, LA drug and N-methyl-2-pyrrolidon solvent with no additives. First, the formul...

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Detalles Bibliográficos
Autores principales: Mashayekhi, Roya, Mobedi, Hamid, Najafi, Jamal, Enayati, Marjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737027/
https://www.ncbi.nlm.nih.gov/pubmed/23856431
http://dx.doi.org/10.1186/2008-2231-21-57