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Identification of resistance of Plasmodium falciparum to artesunate-mefloquine combination in an area along the Thai-Myanmar border: integration of clinico-parasitological response, systemic drug exposure, and in vitro parasite sensitivity
BACKGROUND: A markedly high failure rate of three-day artesunate-mefloquine was observed in the area along the Thai-Myanmar border. METHODS: Identification of Plasmodium falciparum isolates with intrinsic resistance to each component of the artesunate-mefloquine combination was analysed with integra...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737112/ https://www.ncbi.nlm.nih.gov/pubmed/23898808 http://dx.doi.org/10.1186/1475-2875-12-263 |