Rhinovirus 3C Protease Facilitates Specific Nucleoporin Cleavage and Mislocalisation of Nuclear Proteins in Infected Host Cells

Human Rhinovirus (HRV) infection results in shut down of essential cellular processes, in part through disruption of nucleocytoplasmic transport by cleavage of the nucleoporin proteins (Nups) that make up the host cell nuclear pore. Although the HRV genome encodes two proteases (2A and 3C) able to c...

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Detalles Bibliográficos
Autores principales: Walker, Erin J., Younessi, Parisa, Fulcher, Alex J., McCuaig, Robert, Thomas, Belinda J., Bardin, Philip G., Jans, David A., Ghildyal, Reena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737158/
https://www.ncbi.nlm.nih.gov/pubmed/23951130
http://dx.doi.org/10.1371/journal.pone.0071316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737158/
https://www.ncbi.nlm.nih.gov/pubmed/23951130
http://dx.doi.org/10.1371/journal.pone.0071316

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