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The Genetic Architecture of Methotrexate Toxicity Is Similar in Drosophila melanogaster and Humans
The severity of the toxic side effects of chemotherapy varies among patients, and much of this variation is likely genetically based. Here, we use the model system Drosophila melanogaster to genetically dissect the toxicity of methotrexate (MTX), a drug used primarily to treat childhood acute lympho...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737169/ https://www.ncbi.nlm.nih.gov/pubmed/23733889 http://dx.doi.org/10.1534/g3.113.006619 |