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Evolutionarily Stable Attenuation by Genome Rearrangement in a Virus
Live, attenuated viruses provide many of the most effective vaccines. For the better part of a century, the standard method of attenuation has been viral growth in novel environments, whereby the virus adapts to the new environment but incurs a reduced ability to grow in the original host. The downs...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Genetics Society of America
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737178/ https://www.ncbi.nlm.nih.gov/pubmed/23797106 http://dx.doi.org/10.1534/g3.113.006403 |