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Gag-Positive Reservoir Cells Are Susceptible to HIV-Specific Cytotoxic T Lymphocyte Mediated Clearance In Vitro and Can Be Detected In Vivo

Resting CD4+ T cells infected with HIV persist in the presence of suppressive anti-viral therapy (ART) and are barriers to a cure. One potential curative approach, therapeutic vaccination, is fueled by recognition of the ability of a subset of elite controllers (EC) to control virus without therapy...

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Detalles Bibliográficos
Autores principales: Graf, Erin H., Pace, Matthew J., Peterson, Bennett A., Lynch, Lindsay J., Chukwulebe, Steve B., Mexas, Angela M., Shaheen, Farida, Martin, Jeffrey N., Deeks, Steven G., Connors, Mark, Migueles, Stephen A., O’Doherty, Una
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737195/
https://www.ncbi.nlm.nih.gov/pubmed/23951263
http://dx.doi.org/10.1371/journal.pone.0071879