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Aurora B but Not Rho/MLCK Signaling Is Required for Localization of Diphosphorylated Myosin II Regulatory Light Chain to the Midzone in Cytokinesis

Non-muscle myosin II is stimulated by monophosphorylation of its regulatory light chain (MRLC) at Ser19 (1P-MRLC). MRLC diphosphorylation at Thr18/Ser19 (2P-MRLC) further enhances the ATPase activity of myosin II. Phosphorylated MRLCs localize to the contractile ring and regulate cytokinesis as subu...

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Detalles Bibliográficos
Autores principales: Kondo, Tomo, Isoda, Rieko, Ookusa, Takayuki, Kamijo, Keiju, Hamao, Kozue, Hosoya, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737224/
https://www.ncbi.nlm.nih.gov/pubmed/23951055
http://dx.doi.org/10.1371/journal.pone.0070965