Mechanical Stretch Increases MMP-2 Production in Vascular Smooth Muscle Cells via Activation of PDGFR-β/Akt Signaling Pathway

Increased blood pressure, leading to mechanical stress on vascular smooth muscle cells (VSMC), is a known risk factor for vascular remodeling via increased activity of matrix metalloproteinase (MMP) within the vascular wall. This study aimed to identify cell surface mechanoreceptors and intracellula...

Descripción completa

Detalles Bibliográficos
Autores principales: Seo, Kyo Won, Lee, Seung Jin, Kim, Yun Hak, Bae, Jin Ung, Park, So Youn, Bae, Sun Sik, Kim, Chi Dae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737227/
https://www.ncbi.nlm.nih.gov/pubmed/23950935
http://dx.doi.org/10.1371/journal.pone.0070437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737227/
https://www.ncbi.nlm.nih.gov/pubmed/23950935
http://dx.doi.org/10.1371/journal.pone.0070437

Ejemplares similares