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Novel Dicarboxylate Selectivity in an Insect Glutamate Transporter Homolog

Mammals express seven transporters from the SLC1 (solute carrier 1) gene family, including five acidic amino acid transporters (EAAT1–5) and two neutral amino acid transporters (ASCT1–2). In contrast, insects of the order Diptera possess only two SLC1 genes. In this work we show that in the mosquito...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Rascoe, Avi M., Holley, David C., Gouaux, Eric, Kavanaugh, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737229/
https://www.ncbi.nlm.nih.gov/pubmed/23951049
http://dx.doi.org/10.1371/journal.pone.0070947