PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes

Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a negative regulator of T-cell activation associated with several autoimmune diseases, including systemic lupus erythematosus (SLE). Missense rs2476601 is associated with SLE in individuals with European ancestry. Since the rs2476601 risk...

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Detalles Bibliográficos
Autores principales: Namjou, Bahram, Kim-Howard, Xana, Sun, Celi, Adler, Adam, Chung, Sharon A., Kaufman, Kenneth M., Kelly, Jennifer A., Glenn, Stuart B., Guthridge, Joel M., Scofield, Robert H., Kimberly, Robert P., Brown, Elizabeth E., Alarcón, Graciela S., Edberg, Jeffrey C., Kim, Jae-Hoon, Choi, Jiyoung, Ramsey-Goldman, Rosalind, Petri, Michelle A., Reveille, John D., Vilá, Luis M., Boackle, Susan A., Freedman, Barry I., Tsao, Betty P., Langefeld, Carl D., Vyse, Timothy J., Jacob, Chaim O., Pons-Estel, Bernardo, Niewold, Timothy B., Moser Sivils, Kathy L., Merrill, Joan T., Anaya, Juan-Manuel, Gilkeson, Gary S., Gaffney, Patrick M., Bae, Sang-Cheol, Alarcón-Riquelme, Marta E., Harley, John B., Criswell, Lindsey A., James, Judith A., Nath, Swapan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737240/
https://www.ncbi.nlm.nih.gov/pubmed/23950893
http://dx.doi.org/10.1371/journal.pone.0069404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737240/
https://www.ncbi.nlm.nih.gov/pubmed/23950893
http://dx.doi.org/10.1371/journal.pone.0069404

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