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The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems

CRISPR-Cas is a rapidly evolving RNA-mediated adaptive immune system that protects bacteria and archaea against mobile genetic elements. The system relies on the activity of short mature CRISPR RNAs (crRNAs) that guide Cas protein(s) to silence invading nucleic acids. A set of CRISPR-Cas, type II, r...

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Detalles Bibliográficos
Autores principales: Chylinski, Krzysztof, Le Rhun, Anaïs, Charpentier, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737331/
https://www.ncbi.nlm.nih.gov/pubmed/23563642
http://dx.doi.org/10.4161/rna.24321