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The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems
CRISPR-Cas is a rapidly evolving RNA-mediated adaptive immune system that protects bacteria and archaea against mobile genetic elements. The system relies on the activity of short mature CRISPR RNAs (crRNAs) that guide Cas protein(s) to silence invading nucleic acids. A set of CRISPR-Cas, type II, r...
Autores principales: | Chylinski, Krzysztof, Le Rhun, Anaïs, Charpentier, Emmanuelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737331/ https://www.ncbi.nlm.nih.gov/pubmed/23563642 http://dx.doi.org/10.4161/rna.24321 |
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