CRISPR-Cas systems preferentially target the leading regions of MOB(F) conjugative plasmids

Most prokaryotes contain CRISPR-Cas immune systems that provide protection against mobile genetic elements. We have focused on the ability of CRISPR-Cas to block plasmid conjugation, and analyzed the position of target sequences (protospacers) on conjugative plasmids. The analysis reveals that proto...

Descripción completa

Detalles Bibliográficos
Autores principales: Westra, Edze R., Staals, Raymond H.J., Gort, Gerrit, Høgh, Søren, Neumann, Sarah, de la Cruz, Fernando, Fineran, Peter C., Brouns, Stan J.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737333/
https://www.ncbi.nlm.nih.gov/pubmed/23535265
http://dx.doi.org/10.4161/rna.24202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737333/
https://www.ncbi.nlm.nih.gov/pubmed/23535265
http://dx.doi.org/10.4161/rna.24202

Ejemplares similares