Cargando…

CRISPR-Cas systems preferentially target the leading regions of MOB(F) conjugative plasmids

Most prokaryotes contain CRISPR-Cas immune systems that provide protection against mobile genetic elements. We have focused on the ability of CRISPR-Cas to block plasmid conjugation, and analyzed the position of target sequences (protospacers) on conjugative plasmids. The analysis reveals that proto...

Descripción completa

Detalles Bibliográficos
Autores principales:	Westra, Edze R., Staals, Raymond H.J., Gort, Gerrit, Høgh, Søren, Neumann, Sarah, de la Cruz, Fernando, Fineran, Peter C., Brouns, Stan J.J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2013
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737333/ https://www.ncbi.nlm.nih.gov/pubmed/23535265 http://dx.doi.org/10.4161/rna.24202

Ejemplares similares

Adaptation by Type V-A and V-B CRISPR-Cas Systems Demonstrates Conserved Protospacer Selection Mechanisms Between Diverse CRISPR-Cas Types
por: Wu, Wen Y., et al.
Publicado: (2022)

Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity
por: Watson, Bridget N. J., et al.
Publicado: (2019)

Interference-driven spacer acquisition is dominant over naive and primed adaptation in a native CRISPR–Cas system
por: Staals, Raymond H. J., et al.
Publicado: (2016)

Type I-E CRISPR-Cas Systems Discriminate Target from Non-Target DNA through Base Pairing-Independent PAM Recognition
por: Westra, Edze R., et al.
Publicado: (2013)

Modulating CRISPR-Cas Genome Editing Using Guide-Complementary DNA Oligonucleotides
por: Swartjes, Thomas, et al.
Publicado: (2022)

High viral abundance and low diversity are associated with increased CRISPR-Cas prevalence across microbial ecosystems
por: Meaden, Sean, et al.
Publicado: (2022)

Removal of AMR plasmids using a mobile, broad host-range CRISPR-Cas9 delivery tool
por: Walker-Sünderhauf, David, et al.
Publicado: (2023)

A capture approach for supercoiled plasmid DNA using a triplex-forming oligonucleotide
por: Ruigrok, Vincent J. B., et al.
Publicado: (2013)

The Cpf1 CRISPR-Cas protein expands genome-editing tools
por: Fagerlund, Robert D., et al.
Publicado: (2015)

CRISPR-Cas-Mediated Phage Resistance Enhances Horizontal Gene Transfer by Transduction
por: Watson, Bridget N. J., et al.
Publicado: (2018)

Targeting of temperate phages drives loss of type I CRISPR-Cas systems
por: Rollie, Clare, et al.
Publicado: (2020)

CRISPR-Cas systems are widespread accessory elements across bacterial and archaeal plasmids
por: Pinilla-Redondo, Rafael, et al.
Publicado: (2021)

CRISPR-Cas antimicrobials: Challenges and future prospects
por: Pursey, Elizabeth, et al.
Publicado: (2018)

It is unclear how important CRISPR-Cas systems are for protecting natural populations of bacteria against infections by mobile genetic elements
por: Westra, Edze R., et al.
Publicado: (2020)

Anti-CRISPR Phages Cooperate to Overcome CRISPR-Cas Immunity
por: Landsberger, Mariann, et al.
Publicado: (2018)

The effect of bacterial mutation rate on the evolution of CRISPR-Cas adaptive immunity
por: Chevallereau, Anne, et al.
Publicado: (2019)

Quorum Sensing Controls Adaptive Immunity through the Regulation of Multiple CRISPR-Cas Systems
por: Patterson, Adrian G., et al.
Publicado: (2016)

CRISPR-Cas immunity leads to a coevolutionary arms race between Streptococcus thermophilus and lytic phage
por: Common, Jack, et al.
Publicado: (2019)

Recombination between phages and CRISPR-cas loci facilitates horizontal gene transfer in staphylococci
por: Varble, Andrew, et al.
Publicado: (2019)

Editor's cut: DNA cleavage by CRISPR RNA-guided nucleases Cas9 and Cas12a
por: Swartjes, Thomas, et al.
Publicado: (2020)

CRISPRDetect: A flexible algorithm to define CRISPR arrays
por: Biswas, Ambarish, et al.
Publicado: (2016)

Prophages are associated with extensive CRISPR–Cas auto-immunity
por: Nobrega, Franklin L, et al.
Publicado: (2020)

Conserved motifs in the CRISPR leader sequence control spacer acquisition levels in Type I-D CRISPR-Cas systems
por: Kieper, Sebastian N, et al.
Publicado: (2019)

Shooting the messenger: RNA-targetting CRISPR-Cas systems
por: Zhu, Yifan, et al.
Publicado: (2018)

Cas4–Cas1 fusions drive efficient PAM selection and control CRISPR adaptation
por: Almendros, Cristóbal, et al.
Publicado: (2019)

The diverse arsenal of type III CRISPR–Cas-associated CARF and SAVED effectors
por: Steens, Jurre A., et al.
Publicado: (2022)

Addiction systems antagonize bacterial adaptive immunity
por: van Sluijs, Lisa, et al.
Publicado: (2019)

MobC of conjugative RA3 plasmid from IncU group autoregulates the expression of bicistronic mobC-nic operon and stimulates conjugative transfer
por: Godziszewska, Jolanta, et al.
Publicado: (2014)

Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer
por: Richter, Corinna, et al.
Publicado: (2014)

Bacteriophages suppress CRISPR–Cas immunity using RNA-based anti-CRISPRs
por: Camara-Wilpert, Sarah, et al.
Publicado: (2023)

Ordering the mob: Insights into replicon and MOB typing schemes from analysis of a curated dataset of publicly available plasmids
por: Orlek, Alex, et al.
Publicado: (2017)

Cas4 Facilitates PAM-Compatible Spacer Selection during CRISPR Adaptation
por: Kieper, Sebastian N., et al.
Publicado: (2018)

PAM-repeat associations and spacer selection preferences in single and co-occurring CRISPR-Cas systems
por: Vink, Jochem N. A., et al.
Publicado: (2021)

Structure of a type IV CRISPR-Cas ribonucleoprotein complex
por: Zhou, Yi, et al.
Publicado: (2021)

Single cell variability of CRISPR‐Cas interference and adaptation
por: McKenzie, Rebecca E, et al.
Publicado: (2022)

Type IV CRISPR–Cas systems are highly diverse and involved in competition between plasmids
por: Pinilla-Redondo, Rafael, et al.
Publicado: (2020)

Function and Regulation of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) / CRISPR Associated (Cas) Systems
por: Richter, Corinna, et al.
Publicado: (2012)

CRISPR sabotage
por: van der Oost, John, et al.
Publicado: (2015)

A Campylobacter integrative and conjugative element with a CRISPR-Cas9 system targeting competing plasmids: a history of plasmid warfare?
por: van Vliet, Arnoud H. M., et al.
Publicado: (2021)

CRISPRTarget: Bioinformatic prediction and analysis of crRNA targets
por: Biswas, Ambarish, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_m3htl7kp5212pml2nhj9jp03jq