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Structure of the archaeal Cascade subunit Csa5: Relating the small subunits of CRISPR effector complexes

The Cascade complex for CRISPR-mediated antiviral immunity uses CRISPR RNA (crRNA) to target invading DNA species from mobile elements such as viruses, leading to their destruction. The core of the Cascade effector complex consists of the Cas5 and Cas7 subunits, which are widely conserved in prokary...

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Detalles Bibliográficos
Autores principales: Reeks, Judith, Graham, Shirley, Anderson, Linzi, Liu, Huanting, White, Malcolm F., Naismith, James H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737334/
https://www.ncbi.nlm.nih.gov/pubmed/23846216
http://dx.doi.org/10.4161/rna.23854