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CRISPRTarget: Bioinformatic prediction and analysis of crRNA targets

The bacterial and archaeal CRISPR/Cas adaptive immune system targets specific protospacer nucleotide sequences in invading organisms. This requires base pairing between processed CRISPR RNA and the target protospacer. For type I and II CRISPR/Cas systems, protospacer adjacent motifs (PAM) are essent...

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Detalles Bibliográficos
Autores principales: Biswas, Ambarish, Gagnon, Joshua N., Brouns, Stan J.J., Fineran, Peter C., Brown, Chris M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737339/
https://www.ncbi.nlm.nih.gov/pubmed/23492433
http://dx.doi.org/10.4161/rna.24046