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Programmable plasmid interference by the CRISPR-Cas system in Thermococcus kodakarensis

CRISPR-Cas systems are RNA-guided immune systems that protect prokaryotes against viruses and other invaders. The CRISPR locus encodes crRNAs that recognize invading nucleic acid sequences and trigger silencing by the associated Cas proteins. There are multiple CRISPR-Cas systems with distinct compo...

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Detalles Bibliográficos
Autores principales: Elmore, Joshua R., Yokooji, Yuusuke, Sato, Takaaki, Olson, Sara, Glover, III, Claiborne V.C., Graveley, Brenton R., Atomi, Haruyuki, Terns, Rebecca M., Terns, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737340/
https://www.ncbi.nlm.nih.gov/pubmed/23535213
http://dx.doi.org/10.4161/rna.24084