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Optogenetic Control of PIP(3): PIP(3) Is Sufficient to Induce the Actin-Based Active Part of Growth Cones and Is Regulated via Endocytosis
Phosphatidylinositol-3,4,5-trisphosphate (PIP(3)) is highly regulated in a spatiotemporal manner and plays multiple roles in individual cells. However, the local dynamics and primary functions of PIP(3) in developing neurons remain unclear because of a lack of techniques for manipulating PIP(3) spat...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737352/ https://www.ncbi.nlm.nih.gov/pubmed/23951027 http://dx.doi.org/10.1371/journal.pone.0070861 |