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Optogenetic Control of PIP(3): PIP(3) Is Sufficient to Induce the Actin-Based Active Part of Growth Cones and Is Regulated via Endocytosis

Phosphatidylinositol-3,4,5-trisphosphate (PIP(3)) is highly regulated in a spatiotemporal manner and plays multiple roles in individual cells. However, the local dynamics and primary functions of PIP(3) in developing neurons remain unclear because of a lack of techniques for manipulating PIP(3) spat...

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Detalles Bibliográficos
Autores principales: Kakumoto, Toshiyuki, Nakata, Takao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737352/
https://www.ncbi.nlm.nih.gov/pubmed/23951027
http://dx.doi.org/10.1371/journal.pone.0070861