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RNAi Mediated Tiam1 Gene Knockdown Inhibits Invasion of Retinoblastoma

T lymphoma invasion and metastasis protein (Tiam1) is up-regulated in variety of cancers and its expression level is related to metastatic potential of the type of cancer. Earlier, Tiam1 was shown to be overexpressed in retinoblastoma (RB) and we hypothesized that it was involved in invasiveness of...

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Detalles Bibliográficos
Autores principales: Subramanian, Nithya, Navaneethakrishnan, Saranya, Biswas, Jyotirmay, Kanwar, Rupinder K., Kanwar, Jagat R., Krishnakumar, Subramanian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737373/
https://www.ncbi.nlm.nih.gov/pubmed/23950931
http://dx.doi.org/10.1371/journal.pone.0070422