Comparison of IHC, FISH and RT-PCR Methods for Detection of ALK Rearrangements in 312 Non-Small Cell Lung Cancer Patients in Taiwan

BACKGROUND: Recently Echinoderm microtubule-associated protein-like 4- anaplastic lymphoma kinase (EML4-ALK) fusion gene has become an important biomarker for ALK tyrosine kinase inhibitor (crizotinib) treatment in NSCLC. However, the best detection method and the significance of EML4-ALK variant ty...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yi-Cheng, Chang, Il-Chi, Wang, Chi-Liang, Chen, Tai-Di, Chen, Ya-Ting, Liu, Hui-Ping, Chu, Yen, Chiu, Yu-Ting, Wu, Tzu-Hua, Chou, Li-Hui, Chen, Yi-Rong, Huang, Shiu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737393/
https://www.ncbi.nlm.nih.gov/pubmed/23951022
http://dx.doi.org/10.1371/journal.pone.0070839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737393/
https://www.ncbi.nlm.nih.gov/pubmed/23951022
http://dx.doi.org/10.1371/journal.pone.0070839

Ejemplares similares