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The Structure of Herpesvirus Fusion Glycoprotein B-Bilayer Complex Reveals the Protein-Membrane and Lateral Protein-Protein Interaction

Glycoprotein B (gB) is a key component of the complex herpesvirus fusion machinery. We studied membrane interaction of two gB ectodomain forms and present an electron cryotomography structure of the gB-bilayer complex. The two forms differed in presence or absence of the membrane proximal region (MP...

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Detalles Bibliográficos
Autores principales: Maurer, Ulrike E., Zeev-Ben-Mordehai, Tzviya, Pandurangan, Arun Prasad, Cairns, Tina M., Hannah, Brian P., Whitbeck, J. Charles, Eisenberg, Roselyn J., Cohen, Gary H., Topf, Maya, Huiskonen, Juha T., Grünewald, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737472/
https://www.ncbi.nlm.nih.gov/pubmed/23850455
http://dx.doi.org/10.1016/j.str.2013.05.018