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The Role of Salt Bridges, Charge Density, and Subunit Flexibility in Determining Disassembly Routes of Protein Complexes

Mass spectrometry can be used to characterize multiprotein complexes, defining their subunit stoichiometry and composition following solution disruption and collision-induced dissociation (CID). While CID of protein complexes in the gas phase typically results in the dissociation of unfolded subunit...

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Detalles Bibliográficos
Autores principales: Hall, Zoe, Hernández, Helena, Marsh, Joseph A., Teichmann, Sarah A., Robinson, Carol V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737473/
https://www.ncbi.nlm.nih.gov/pubmed/23850452
http://dx.doi.org/10.1016/j.str.2013.06.004