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Enhancer networks revealed by correlated DNAse hypersensitivity states of enhancers

Mammalian gene expression is often regulated by distal enhancers. However, little is known about higher order functional organization of enhancers. Using ∼100 K P300-bound regions as candidate enhancers, we investigated their correlated activity across 72 cell types based on DNAse hypersensitivity....

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Detalles Bibliográficos
Autores principales: Malin, Justin, Aniba, Mohamed Radhouane, Hannenhalli, Sridhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737527/
https://www.ncbi.nlm.nih.gov/pubmed/23700312
http://dx.doi.org/10.1093/nar/gkt374