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UGA codon position-dependent incorporation of selenocysteine into mammalian selenoproteins
It is thought that the SelenoCysteine Insertion Sequence (SECIS) element and UGA codon are sufficient for selenocysteine (Sec) insertion. However, we found that UGA supported Sec insertion only at its natural position or in its close proximity in mammalian thioredoxin reductase 1 (TR1). In contrast,...
Autores principales: | Turanov, Anton A., Lobanov, Alexei V., Hatfield, Dolph L., Gladyshev, Vadim N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737529/ https://www.ncbi.nlm.nih.gov/pubmed/23716634 http://dx.doi.org/10.1093/nar/gkt409 |
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