Structural dynamics of possible late-stage intermediates in folding of quadruplex DNA studied by molecular simulations

Explicit solvent molecular dynamics simulations have been used to complement preceding experimental and computational studies of folding of guanine quadruplexes (G-DNA). We initiate early stages of unfolding of several G-DNAs by simulating them under no-salt conditions and then try to fold them back...

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Detalles Bibliográficos
Autores principales: Stadlbauer, Petr, Krepl, Miroslav, Cheatham, Thomas E., Koča, Jaroslav, Šponer, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737530/
https://www.ncbi.nlm.nih.gov/pubmed/23700306
http://dx.doi.org/10.1093/nar/gkt412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737530/
https://www.ncbi.nlm.nih.gov/pubmed/23700306
http://dx.doi.org/10.1093/nar/gkt412

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