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Structural dynamics of possible late-stage intermediates in folding of quadruplex DNA studied by molecular simulations
Explicit solvent molecular dynamics simulations have been used to complement preceding experimental and computational studies of folding of guanine quadruplexes (G-DNA). We initiate early stages of unfolding of several G-DNAs by simulating them under no-salt conditions and then try to fold them back...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737530/ https://www.ncbi.nlm.nih.gov/pubmed/23700306 http://dx.doi.org/10.1093/nar/gkt412 |