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Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I

The transcription-export complex (TREX) couples mRNA transcription, processing and nuclear export. We found that CFIm68, a large subunit of a heterotetrameric protein complex mammalian cleavage factor I (CFIm), which is implicated in alternative polyadenylation site choice, co-purified with Thoc5, a...

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Detalles Bibliográficos
Autores principales: Katahira, Jun, Okuzaki, Daisuke, Inoue, Hitomi, Yoneda, Yoshihiro, Maehara, Kazumitsu, Ohkawa, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737531/
https://www.ncbi.nlm.nih.gov/pubmed/23685434
http://dx.doi.org/10.1093/nar/gkt414