Cargando…

Human TREX component Thoc5 affects alternative polyadenylation site choice by recruiting mammalian cleavage factor I

The transcription-export complex (TREX) couples mRNA transcription, processing and nuclear export. We found that CFIm68, a large subunit of a heterotetrameric protein complex mammalian cleavage factor I (CFIm), which is implicated in alternative polyadenylation site choice, co-purified with Thoc5, a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Katahira, Jun, Okuzaki, Daisuke, Inoue, Hitomi, Yoneda, Yoshihiro, Maehara, Kazumitsu, Ohkawa, Yasuyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737531/ https://www.ncbi.nlm.nih.gov/pubmed/23685434 http://dx.doi.org/10.1093/nar/gkt414

Ejemplares similares

THOC5 controls 3′end-processing of immediate early genes via interaction with polyadenylation specific factor 100 (CPSF100)
por: Tran, Doan Duy Hai, et al.
Publicado: (2014)

Aly and THO are required for assembly of the human TREX complex and association of TREX components with the spliced mRNA
por: Chi, Binkai, et al.
Publicado: (2013)

Mud2 functions in transcription by recruiting the Prp19 and TREX complexes to transcribed genes
por: Minocha, Rashmi, et al.
Publicado: (2018)

hnRNPC regulates cancer-specific alternative cleavage and polyadenylation profiles
por: Fischl, Harry, et al.
Publicado: (2019)

A Sub-Element in PRE enhances nuclear export of intronless mRNAs by recruiting the TREX complex via ZC3H18
por: Chi, Binkai, et al.
Publicado: (2014)

NXF2 is involved in cytoplasmic mRNA dynamics through interactions with motor proteins
por: Takano, Keizo, et al.
Publicado: (2007)

Knock-down of 25 kDa subunit of cleavage factor Im in Hela cells alters alternative polyadenylation within 3′-UTRs
por: Kubo, Tomohiro, et al.
Publicado: (2006)

SWI/SNF interacts with cleavage and polyadenylation factors and facilitates pre-mRNA 3′ end processing
por: Yu, Simei, et al.
Publicado: (2018)

The structural basis of CstF-77 modulation of cleavage and polyadenylation through stimulation of CstF-64 activity
por: Grozdanov, Petar N, et al.
Publicado: (2018)

Landscape of RNA polyadenylation in E. coli
por: Maes, Alexandre, et al.
Publicado: (2017)

Sequence-dependent recruitment of SRSF1 and SRSF7 to intronless lncRNA NKILA promotes nuclear export via the TREX/TAP pathway
por: Khan, Misbah, et al.
Publicado: (2021)

Nuclear RNA export factor 7 is localized in processing bodies and neuronal RNA granules through interactions with shuttling hnRNPs
por: Katahira, Jun, et al.
Publicado: (2008)

Exportin-5 orthologues are functionally divergent among species
por: Shibata, Satoshi, et al.
Publicado: (2006)

Quantification of stochastic noise of splicing and polyadenylation in Entamoeba histolytica
por: Hon, Chung-Chau, et al.
Publicado: (2013)

THOC5/FMIP, an mRNA export TREX complex protein, is essential for hematopoietic primitive cell survival in vivo
por: Mancini, Annalisa, et al.
Publicado: (2010)

ORC interacts with THSC/TREX-2 and its subunits promote Nxf1 association with mRNP and mRNA export in Drosophila
por: Kopytova, Daria, et al.
Publicado: (2016)

Global analysis of the mammalian RNA degradome reveals widespread miRNA-dependent and miRNA-independent endonucleolytic cleavage
por: Bracken, Cameron P., et al.
Publicado: (2011)

RNA polyadenylation and degradation in different Archaea; roles of the exosome and RNase R
por: Portnoy, Victoria, et al.
Publicado: (2006)

Chromatin-bound CRM1 recruits SET-Nup214 and NPM1c onto HOX clusters causing aberrant HOX expression in leukemia cells
por: Oka, Masahiro, et al.
Publicado: (2019)

Polyadenylation of a functional mRNA controls gene expression in Escherichia coli
por: Joanny, Géraldine, et al.
Publicado: (2007)

Differential usage of transcriptional start sites and polyadenylation sites in FMR1 premutation alleles(†)
por: Tassone, Flora, et al.
Publicado: (2011)

Recognition of Transcription Termination Signal by the Nuclear Polyadenylated RNA-binding (NAB) 3 Protein
por: Hobor, Fruzsina, et al.
Publicado: (2011)

Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes
por: Oka, Masahiro, et al.
Publicado: (2016)

A compendium of conserved cleavage and polyadenylation events in mammalian genes
por: Wang, Ruijia, et al.
Publicado: (2018)

LRPPRC/SLIRP suppresses PNPase-mediated mRNA decay and promotes polyadenylation in human mitochondria
por: Chujo, Takeshi, et al.
Publicado: (2012)

Exploration of nucleosome positioning patterns in transcription factor function
por: Maehara, Kazumitsu, et al.
Publicado: (2016)

MicroRNA-mediated up-regulation of an alternatively polyadenylated variant of the mouse cytoplasmic β-actin gene
por: Ghosh, Tanay, et al.
Publicado: (2008)

ElrA binding to the 3′UTR of cyclin E1 mRNA requires polyadenylation elements
por: Slevin, Michael K., et al.
Publicado: (2007)

Regulatory mechanisms for 3′-end alternative splicing and polyadenylation of the Glial Fibrillary Acidic Protein, GFAP, transcript
por: Blechingberg, Jenny, et al.
Publicado: (2007)

An essential role for Clp1 in assembly of polyadenylation complex CF IA and Pol II transcription termination
por: Haddad, Raphaël, et al.
Publicado: (2012)

siRNAs targeted to certain polyadenylation sites promote specific, RISC-independent degradation of messenger RNAs
por: Vickers, Timothy A., et al.
Publicado: (2012)

Essential role for non-canonical poly(A) polymerase GLD4 in cytoplasmic polyadenylation and carbohydrate metabolism
por: Shin, Jihae, et al.
Publicado: (2017)

Cleavage of model substrates by archaeal RNase P: role of protein cofactors in cleavage-site selection
por: Sinapah, Sylvie, et al.
Publicado: (2011)

A novel source for miR-21 expression through the alternative polyadenylation of VMP1 gene transcripts
por: Ribas, Judit, et al.
Publicado: (2012)

Analysis of C. elegans intestinal gene expression and polyadenylation by fluorescence-activated nuclei sorting and 3′-end-seq
por: Haenni, Simon, et al.
Publicado: (2012)

Non-polyadenylated transcription in embryonic stem cells reveals novel non-coding RNA related to pluripotency and differentiation
por: Livyatan, Ilana, et al.
Publicado: (2013)

Kaposi's sarcoma-associated herpesvirus polyadenylated nuclear RNA: a structural scaffold for nuclear, cytoplasmic and viral proteins
por: Sztuba-Solinska, Joanna, et al.
Publicado: (2017)

Dido3-dependent SFPQ recruitment maintains efficiency in mammalian alternative splicing
por: Mora Gallardo, Carmen, et al.
Publicado: (2019)

The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3′-end processing of animal histone mRNAs
por: Ruepp, Marc-David, et al.
Publicado: (2010)

THOC2 and THOC5 Regulate Stemness and Radioresistance in Triple‐Negative Breast Cancer
por: Bai, Xupeng, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_o6finb1fgbkf3u48kodsq10csb