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Real-time single-molecule tethered particle motion analysis reveals mechanistic similarities and contrasts of Flp site-specific recombinase with Cre and λ Int

Flp, a tyrosine site-specific recombinase coded for by the selfish two micron plasmid of Saccharomyces cerevisiae, plays a central role in the maintenance of plasmid copy number. The Flp recombination system can be manipulated to bring about a variety of targeted DNA rearrangements in its native hos...

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Detalles Bibliográficos
Autores principales: Fan, Hsiu-Fang, Ma, Chien-Hui, Jayaram, Makkuni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737535/
https://www.ncbi.nlm.nih.gov/pubmed/23737451
http://dx.doi.org/10.1093/nar/gkt424