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Enhanced and prolonged baculovirus-mediated expression by incorporating recombinase system and in cis elements: a comparative study

Baculovirus (BV) is a promising gene vector but mediates transient expression. To prolong the expression, we developed a binary system whereby the transgene in the substrate BV was excised by the recombinase (ΦC31o, Cre or FLPo) expressed by a second BV and recombined into smaller minicircle. The re...

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Detalles Bibliográficos
Autores principales: Sung, Li-Yu, Chen, Chiu-Ling, Lin, Shih-Yeh, Hwang, Shiaw-Min, Lu, Chia-Hsin, Li, Kuei-Chang, Lan, Alice S., Hu, Yu-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737544/
https://www.ncbi.nlm.nih.gov/pubmed/23716635
http://dx.doi.org/10.1093/nar/gkt442